College of Agriculture and Bioresources

Research Area(s)

  • Livestock production
  • Environmental sustainability
  • Animal nutrition
  • Epigenetics
  • Developmental programming
  • Molecular genetics
  • Nutrient-gene interactions

Department

Animal and Poultry Sciecne

Research Interests

My research focuses on nutritional epigenetics and developmental programming in livestock, with an emphasis on how maternal nutrition influences fetal development and long-term health outcomes. My research integrates molecular biology, physiology, and genomics to explore the effects of micronutrients and one-carbon metabolites on gene expression and organ development across generations. Through both applied and fundamental approaches, I aim to advance precision agriculture and improve production efficiency in animal production systems.

Education

PhD (Animal Science), University of Saskatchewan

Master of Science (Animal Science), University of Saskatchewan

Bachelor of Science in Agriculture (Animal Science), University of Saskatchewan

Selected Recent Publications

Anas, M., AK. Ward, K. L. McCarthy, P. P. Borowicz, L. P. Reynolds, J. S. Caton, C. R. Dahlen, and W. J. S. Diniz. 2025. Intergenerational effects of maternal rate of body weight gain on the multi-omics hepatic profiles of bovine fetuses. Gene. 936:149082. doi:10.1016/j.gene.2024.149082

Crouse, M. S., R. A. Cushman, C. A. Redifer, B. W. Neville, C. R. Dahlen, J. S. Caton, W. J. S. Diniz, and A. K. Ward. 2024. International symposium on Ruminant Physiology: One-carbon metabolism in beef cattle throughout the production cycle. J. Dairy Sci. 108:7615-7630. doi:10.3168/jds.2024-25784

Anas, M., A. K. Ward, K. L. McCarthy, P. P. Borowicz, L. P. Reynolds, J. S. Caton, C. R. Dahlen, and W. J. S. Diniz. 2024. lncRNA-gene network analysis reveals the effects of early maternal nutrition on mineral homeostasis and energy metabolism in the fetal liver transcriptome of beef heifers. J. Nutr. Biochem. 132:109691. doi:10.1016/j.jnutbio.2024.109691

Kanjanaruch, C., K. A. Bochantin, B. J. D. Ruiz, J. Syring, Y. Entzie, L. King, P. P. Borowicz, M. S. Crouse, J. S. Caton, C. R. Dahlen, A. K. Ward, and L. P. Reynolds. 2024. One-carbon metabolite supplementation to nutrient-restricted beef heifers affects placental vascularity during early pregnancy. J. Anim. Sci. 102:skae044. doi:10.1093/jas/skae044

Safain, K. S., M. S. Crouse, J. G. Syring, Y. L. Entzie, L. E. King, M. R. Hirchert, A. K. Ward, L. P. Reynolds, P. P. Borowicz, C. R. Dahlen, K. C. Swanson, and J. S. Caton. 2024. One-carbon metabolites supplementation and nutrient restriction alter the fetal liver metabolomic profile during early gestation in beef heifers. J. Anim. Sci. 102:skae258. doi:10.1093/jas/skae258

Daneshi, M., J. S. Caton, L. S. Caixeta, Z. Eftekhari, and A. K. Ward. 2023. Expression, regulation, and function of β-defensins in the bovine mammary glands: Current knowledge and future perspectives. Animals. 13:3372. doi:10.3390/ani13213372

Anas, M., W. J. S. Diniz, A. C. B. Menezes, L. P. Reynolds, J. S. Caton, C. R. Dahlen, and A. K. Ward. 2023. Maternal mineral nutrition regulates fetal genomic programming in cattle: A review. Metabolites. 13:593. doi:10.3390/metabo13050593

Diniz, W. J. S., A. K. Ward, K. L. McCarthy, C. J. Kassetas, F. Baumgaertner, L. P. Reynolds, P. P. Borowicz, K. K. Sedivec, J. D. Kirsch, S. T. Dorsam, T. L. Neville, J. C. Forcherio, R. Scott, J. S. Caton, and C. R. Dahlen. 2023. Periconceptual maternal nutrition affects fetal liver programming of energy- and lipid-related genes. Animals. 13:600. doi:10.3390/ani13040600

Reynolds, L. P., W. J. S. Diniz, M. S. Crouse, J. S. Caton, C. R. Dahlen, P. P. Borowicz, and A. K. Ward. 2022. Maternal nutrition and developmental programming of offspring. Reprod. Fertil. Dev. 35:19-26. doi:10.1071/RD22234

Crouse, M. S., J. S. Caton, K. J. Claycombe-Larson, W. J. S. Diniz, A. K. Lindholm-Perry, L. P. Reynolds, C. R. Dahlen, P. P. Borowicz, and A. K. Ward. 2022. Epigenetic modifier supplementation improves mitochondrial respiration and growth rates and alters DNA methylation of bovine embryonic fibroblast cells cultured in divergent energy supply. Front. Genet. 13:1–14. doi:10.3389/fgene.2022.812764

Selected Awards

2024 Open Resources Initiative Award, University of Saskatchewan Students Union (USSU) Teaching Excellence Awards

Funding Sources

USDA National Institute of Food and Agriculture, Agriculture and Food Research Initiative

USDA National Institute of Food and Agriculture, Equipment Grant Program

North Dakota State Board of Agricultural Research and Education

North Dakota Beef Commission

Courses

ANSC 313 – Animal Breeding and Genetics