Picture of  Natacha Hogan

Natacha Hogan Assistant Professor

Address
6D66 - Agriculture Building

Research Area(s)

  • toxicology/environmental health
  • endocrinology
  • ecotoxicology of contaminants in amphibians and fish
  • environment-immune interactions in disease susceptibility
  • strategies for detoxification of animal feed to improve animal health

Department

Animal and Poultry Science

Education

PhD (Biology, Spec. Chemical and Environmental Toxicology), University of Ottawa, Ottawa, ON, Canada (2007)
BSc (Biology), University of Prince Edward Island, Charlottetown, PE, Canada (2000)

Research Interests

Overall, my research program investigates mechanisms underlying toxicity of both natural and anthropogenic toxicants. The ultimate goal of this research is to establish acceptable risk thresholds for toxicants, which can be used by industry or regulatory bodies in efforts to improve environmental quality and animal health.

My research areas include:

  • Hormone cross-regulation and disruption of endocrine signaling affecting development and reproduction
  • Mechanisms of contaminant-induced immune suppression in fish and amphibians – implications for disease susceptibility
  • Effects of dietary mycotoxins on animal performance, focus on immune response, gut health, oxidative stress and organ damage
  • Use of genomic and biochemical techniques to identify and evaluate exposure to environmental contaminants

Selected Publications

Muldoon B and NS Hogan. 2016. Biomarker responses to estrogen and androgen exposure in the brook stickleback (Culaea inconstans: a new bioindicator species for endocrine disrupting compounds. Comparative Biochemistry and Physiology Part C: Toxicology and Pharmacology 180:1-10.

Maxham L, Forzan M, Hogan NS, Vanderstichel R and C Gilroy. 2015. Hematological reference intervals for Xenopus tropicalis with partial use of automatic counting methods and reliability of long-term stored samples. Veterinary Clinical Pathology

Leclair LA, Pohler L, Wiseman SB, He Y, Arens CJ, Giesy JP, Scully S, Wagner BD, van den Heuvel MR, and NS Hogan. 2015. In vitro assessment of endocrine disrupting potential of naphthenic acid fractions derived from oil sands-influenced water. Environmental Science and Technology 49 (9):5743-5752

Kautzman M, Hogan NS, Wickstrom M, T Scott. 2015. Using near infrared transmission to generate sorted fractions of Fusarium infected wheat and their impact on broiler performance. Poultry Science 94(7):1619-28.

Arens CJ, Hogan NS, Kavanagh RJ, Mercer AG, van der Kraak GJ and MR van den Heuvel. 2015. Sublethal effects of aged oil sands affected water on white sucker (Catostomus commersonii). Environmental Toxicology and Chemistry 34:589-599.

Funding Sources

NSERC Discovery Grant
NSERC Collaborative Research and Development Grant
NSERC Engage Grant
Canadian Poultry Research Council of Canada
Canadian Bio-Systems
TransCanada Ltd
Federated Cooperatives Ltd.
Environment Canada

Courses Taught

TOX 402 - Systemic Toxicology
ANBI 420 - Comparative Endocrinology
ANBI 110 - Introductory Animal Bioscience
ANSC 898 - Mycotoxins and Animal Health